Publications
Since the beginning of her career, Dra. Alquézar have contributed to more than 30 papers and one book chapter that accumulate more than 100 citations (Google Scholar h-index 21).
The complete List of her Published Work can be found here: https://www.ncbi.nlm.nih.gov/myncbi/1HMCnKhhq_dcgx/bibliography/public/
Below is shown a list of the10 papers that better represent her research.
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Rodrigez-Periñan G*, de la Encarnación A*, Moreno F, López de Munain A, Martinez A Martín-Requero A, Alquézar C†, Bartolomé F†. Progranulin deficiency induces mitochondrial dysfunction in FTLD-TPD. Enviado a Mol Neurodegener. *Equal contribution. † Corresponding authors. Antioxidants 2022.
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Bartolomé F, Carro E, Alquezar C. Oxidative stress in tauopathies: From cause to therapy. Antioxidants 2022.
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Alquezar C, Schoch KM, Geier EG, Ramos EM, Scrivo A, Li K, Argouarch AR, Mlynarski EE, Dombroski B, DeTure M, Dickson DW, Yokoyama JS, Cuervo AM, Burlingame AL, Schellenberg GD, Miller TM, Miller BL, Kao AW. TSC1 loss-of-function increases risk for tauopathy by inducing tau acetylation and preventing tau clearance via chaperone mediated autophagy. Science Advances. Nov. 5. 2021
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Alquezar C, Shruti A, Kao AW. Tau Post-translational Modifications: Dynamic Transformers of Tau Function, Degradation, and Aggregation. Front. Neurol., 2021 Jan.
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Alquezar C, Felix JB, McCandlish E, Buckley BT, Caparros-Lefebvre D, Karch CM, Golbe LI, Kao AW. Heavy metals contaminating the environment of a progressive supranuclear palsy cluster induce tau accumulation and cell death in cultured neurons. Sci Rep. 2020 Jan 17;10(1):569.
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Olney NT*, Alquezar C*, Ramos EM, Nana AL, Fong JC, Karydas AM, Taylor JB, Stephens ML, Argouarch AR, Van Berlo VA, Dokuru DR, Sherr EH, Jicha GA, Dillon WP, Desikan RS, De May M, Seeley WW, Coppola G, Miller BL, Kao AW. Linking tuberous sclerosis complex, excessive mTOR signaling, and age-related neurodegeneration: a new association between TSC1 mutation and frontotemporal dementia. Acta Neuropathol. 2017 Nov;134(5):813-816. *Equal contribution.
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Alquézar C, de la Encarnación A, Moreno F, López de Munain A, Martín-Requero Á. Progranulin deficiency induces overactivation of WNT5A expression via TNF-α/NF-κB pathway in peripheral cells from frontotemporal dementia-linked granulin mutation carriers. J Psychiatry Neurosci. 2016 Jun;41(4):225-39.
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Alquezar C, Salado IG, de la Encarnación A, Pérez DI, Moreno F, Gil C, de Munain AL, Martínez A, Martín-Requero Á. Targeting TDP-43 phosphorylation by Casein Kinase-1δ inhibitors: a novel strategy for the treatment of frontotemporal dementia. Mol Neurodegener. 2016 Apr 30;11(1):36.
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Alquezar C, Esteras N, de la Encarnación A, Moreno F, López de Munain A, Martín-Requero Á. Increasing progranulin levels and blockade of the ERK1/2 pathway: upstream and downstream strategies for the treatment of progranulin deficient frontotemporal dementia. Eur Neuropsychopharmacol. 2015 Mar;25(3):386-403.
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Alquezar C, Esteras N, Bartolomé F, Merino JJ, Alzualde A, López de Munain A, Martín-Requero Á. Alteration in cell cycle-related proteins in lymphoblasts from carriers of the c.709-1G>A PGRN mutation associated with FTLD-TDP dementia. Neurobiol Aging. 2012 Feb;33(2):429.e7-20.